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PROMPT Registry Articles

Evidence on hereditary-cancer testing, from swab to sequencer.. Explore our collection of expert insights, guides, and the latest updates.

Latest Articles

Maintaining Chain-of-Custody: Specimen Tracking in Multi-Center Registry Studies
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Specimen Chain-of-Custody

Maintaining Chain-of-Custody: Specimen Tracking in Multi-Center Registry Studies

Understanding Specimen Chain-of-Custody Maintaining the integrity and traceability of biological spe...

Evaluating Genetic Testing Kits: Clinical Diagnostics vs. Direct-to-Consumer Genotyping
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Clinical vs Direct-to-Consumer

Evaluating Genetic Testing Kits: Clinical Diagnostics vs. Direct-to-Consumer Genotyping

Genetic testing has become an increasingly accessible tool, offering profound insights into an indiv...

Safeguarding Genomic Integrity: Cold-Chain Handling and Biospecimen Logistics
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Cold-Chain Handling

Safeguarding Genomic Integrity: Cold-Chain Handling and Biospecimen Logistics

The rapidly evolving fields of genomics and personalized medicine depend critically on the quality a...

Standardizing the Bench: How PCR Plates and Reagents Impact Next-Generation Sequencing Yield
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PCR Plates & Reagents

Standardizing the Bench: How PCR Plates and Reagents Impact Next-Generation Sequencing Yield

Next-Generation Sequencing (NGS) has revolutionized genomics, enabling comprehensive analysis of DNA...

The Economics of Precision Medicine: BRCA Testing Cost and Choosing a Multi-Gene Panel
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Choosing a Multi-Gene Panel

The Economics of Precision Medicine: BRCA Testing Cost and Choosing a Multi-Gene Panel

Understanding the Landscape of Genetic Testing Precision medicine offers tailored healthcare solutio...

Sourcing and Vetting DNA Saliva Collection Kits for Large-Scale Registry Studies
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Saliva Collection Kits

Sourcing and Vetting DNA Saliva Collection Kits for Large-Scale Registry Studies

The Crucial Role of Saliva Collection Kits in Genomic Research Large-scale genomic registry studies...

Deciphering the Unknown: A Patient’s Guide to Variants of Uncertain Significance (VUS)
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Variants of Uncertain Significance

Deciphering the Unknown: A Patient’s Guide to Variants of Uncertain Significance (VUS)

Genetic testing has revolutionized our understanding of inherited conditions, offering invaluable in...

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Genetics

Why a bigger panel raises your odds of a VUS

More genes on a test means more places a question mark can appear. Here’s why panel size drives VUS...

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Genetics

Germline vs somatic variants, explained

What separates an inherited germline variant from an acquired somatic one — and why the distinction...

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Genetics

Advances in multi-gene panel sequencing, and what they mean for screening

How next-generation multi-gene panels read many cancer-risk genes at once, how variants are classifi...

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Genetics

Direct-to-consumer vs clinical genetic testing: what actually differs

DTC kits and clinical genetic tests can both name a gene — but they differ in coverage, accuracy, an...

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Genetics

The precision-medicine workflow, clinic to report

A plain-language walk through how a genetic sample becomes a clinical report — sampling, sequencing...

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